IMPORTANT QUESTIONS - LIPID METABOLISM


LAQ:


1. Explain the steps of beta oxidation of palmitic acid, giving energetics and regulation.
2. Describe the reactions of de novo synthesis of fatty acids and how is it regulated.
3. Enumerate the major steps of synthesis of cholesterol. Name the rate limiting step.
4. What are ketone bodies? Explain the reactions leading to their formation. how are they utilized in the body.
5. Describe the pathway for synthesis of TAG.
6. Describe the role of liver in fat metabolism.


SAQ:


1. Explain the role of carnitine in fatty acid transport.
2. Regulation of hormone sensitive lipase.
3. What are the different types of ketone bodies? also mention the diseases in which ketone bodies increase in the body.
4. Important functions of cholesterol.
5. Briefly explain atherosclerosis.
6. What is fatty liver ? Mention the factors leading to fatty liver and the lipotropic factors.
7. Explain lipoproteins. Also mention the role of different type of lipoproteins and their clinical significance. 


Other questions for MBBS students:
1. Oxidation of odd chain fatty acids (SAQ).
2. What is alpha oxidation. (SAQ) 
3. What is omega oxidation. (SAQ)
4. Explain what is methyl malonic aciduria. (SAQ)
5. Explain what is Refsum's disease. (SAQ)
6. Explain the metabolism of adipose tissue in well fed condition and during fasting. (LAQ)
7. What is brown adipose tissue. (SAQ)
8. Mention and explain the different types of hyperlipidemia. Also mention the therapeutic interventions. (LAQ)