Monday, 26 March 2012

IMPORTANT QUESTIONS - METABOLISM OF XENOBIOTICS

LAQ:

1.Explain in detail the different phases of detoxification.

SAQ:

1. Explain the metabolic role of glucuronic acid.
2. Describe detoxification by conjugation.
3. Describe detoxification by oxidation.
4. Describe detoxification by hydrolysis.
5. How is hippuric acid formed. 
6. Explain the role of glutathione in conjugation.
7. Explain the role of cytochrome P450 in detoxification.

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